Corona Vaccine Will be Ready by September?

The Precious of Transformation” Coronavirus… When will the vaccine come out?

Corona 19 has been around for 2 months, but there is no news of vaccine development yet. Why is vaccine development late? This is because the coronavirus, which has a changeless nature, makes the vaccine production process that takes a long time.

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RNA virus, 'mutation' probability up to 1 million times

to make a vaccine, you need to pinpoint the pathogens causing the disease. If you know what a pathogen is, you can make a vaccine using antibodies and antigens. However, the coronavirus constantly changes its appearance and creates confusion. Coronavirus has an RNA gene that causes respiratory disease in mammals and birds. 'DNA' as we know well is stable because it stores genetic information, whereas 'RNA', which carries genetic information, is unstable (open) because it needs to react well with other substances. Therefore, it has the property of changing its appearance from time to time, and these RNAs even make mutant genes.

In fact, RNA viruses are up to one million times more likely to develop mutant genes than DNA. As it changes its appearance well, it adapts well to other types, resulting in 'interspecies transmission' between mammals and birds, and even changing into a form with strong infectivity and high mortality, resulting in 'new coronavirus'. Professor Jung-Hyun Choi of Infection Medicine at Eunpyeong St. Mary's Hospital said, "It is necessary to have a common structure to make antibodies and develop a vaccine." In the case of a changeable coronavirus, there is no structure that can be targeted. " He said, "There is no vaccine developed at this time because the virus mutation is so frequent."

Other Types

SARS (Severe Acute Respiratory Syndrome) and MERS (MERS, Middle East Respiratory Syndrome) are both coronavirus respiratory diseases. Two infectious diseases that have been around for a long time have no vaccine because of the nature of the coronavirus like chameleon. Professor Kim Woo-joo of the Department of Infection Medicine at Korea Daeguro Hospital explained, “It is difficult to accumulate data because new coronavirus disease occurs every few decades.” “It is the reason why the coronavirus vaccine is still experiencing difficulties in development.”

A difficult vaccine right now ... “It is best to follow the infection rules”

It is difficult to expect a corona19 vaccine right now. This is because the original vaccine development takes a long time and money. To make a vaccine, you need to find an antigen and then go through a complex clinical process: animal experiments-human phase 1-human phase 2-human phase 3. Prof. Kim Woo-ju said, “It takes 10 ~ 15 years to make a vaccine and it costs about 1 trillion won. .

It is said that the H1N1 vaccine was made in a short period of time, but the H1N1 flu was a lucky case. Professor Kim Woo-ju said, "We only needed to change the antigens in the factory and the production technology of influenza vaccines that existed in the past." Coronavirus also said it would have been faster if it had a vaccine platform.

Instead of waiting for vaccine development, experts emphasize that it is best to follow infection prevention practices. Professor Choi Jung-hyun said, “After all, avoiding many places, wearing a mask well, and making hand disinfection and washing your hands a fundamental way to prevent corona19”.